INT259621

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Serpinc1, Mmp12) peptidase activity (Mmp12) extracellular space (Serpinc1)
proteinaceous extracellular matrix (Mmp12)
Serpinc1 (Mus musculus)
Mmp12 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 58 52.80 Quite High
metalloproteinase 38 35.76 Quite Low
fibrosis 9 10.52 Low Low
Inflammatory mediators 9 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Burns 1 91.68 High High
Pulmonary Disease 88 85.12 High High
Death 2 77.36 Quite High
Apoptosis 14 75.20 Quite High
Nicotine Addiction 4 69.20 Quite High
INFLAMMATION 50 52.80 Quite High
Pulmonary Emphysema 5 22.56 Low Low
Emphysema 7 18.28 Low Low
Fibrosis 11 10.52 Low Low
Pneumonia 19 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies of mice genetically deficient in proteinases in these acute exposure models have identified critical roles for MMP-12 in regulating PMN influx and for thrombin and plasmin in regulating MMP-12 production (Figure 2).
thrombin Regulation (regulating) of Gene_expression (production) of MMP-12
1) Confidence 0.01 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2629972 Disease Relevance 0.89 Pain Relevance 0.03

General Comments

This test has worked.

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