INT259629

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Adam17, Timp3) cytoplasm (Adam17, Timp3) peptidase activity (Adam17)
proteinaceous extracellular matrix (Timp3) cell motility (Adam17) cell adhesion (Adam17)
Adam17 (Mus musculus)
Timp3 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 38 90.40 High High
Inflammation 58 52.20 Quite High
Inflammatory mediators 9 5.00 Very Low Very Low Very Low
fibrosis 9 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Emphysema 5 82.68 Quite High
INFLAMMATION 50 52.20 Quite High
Adhesions 2 51.56 Quite High
Pulmonary Disease 88 24.52 Low Low
Pneumonia 19 5.00 Very Low Very Low Very Low
Apoptosis 14 5.00 Very Low Very Low Very Low
Fibrosis 11 5.00 Very Low Very Low Very Low
Emphysema 7 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Lung Injury 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, ADAM-17 is resistant to inhibition by TIMPs-1 and -2 but not TIMP-3 (Amour et al 1998), and MT1-MMP is resistant to inhibition by TIMP-1 but not TIMP-2 (DÂ’Ortho et al 1998).
ADAM-17 Neg (inhibition) Binding (inhibition) of TIMP-3
1) Confidence 0.01 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2629972 Disease Relevance 0.19 Pain Relevance 0.11

General Comments

This test has worked.

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