INT259635

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Context Info
Confidence 0.13
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Plau, PLG) extracellular space (Plau, PLG) extracellular region (Plau, PLG)
plasma membrane (PLG) kinase activity (Plau)
Anatomy Link Frequency
lung 1
Plau (Mus musculus)
PLG (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 9 74.28 Quite High
Inflammation 58 47.56 Quite Low
metalloproteinase 38 12.08 Low Low
fibrosis 9 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 11 97.48 Very High Very High Very High
INFLAMMATION 50 73.88 Quite High
Apoptosis 14 48.40 Quite Low
Pulmonary Disease 88 38.80 Quite Low
Pneumonia 19 5.00 Very Low Very Low Very Low
Emphysema 7 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Lung Injury 6 5.00 Very Low Very Low Very Low
Pulmonary Emphysema 5 5.00 Very Low Very Low Very Low
Nicotine Addiction 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus by generating plasmin, uPA regulates not only fibrinolysis, but also ECM degradation and fibrotic processes in the lung.


uPA Positive_regulation (generating) of plasmin in lung associated with fibrosis
1) Confidence 0.13 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2629972 Disease Relevance 0.22 Pain Relevance 0.06

General Comments

This test has worked.

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