INT259832

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Context Info
Confidence 0.23
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.07
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Slc12a3) transport (Slc12a3) plasma membrane (Slc12a3)
transmembrane transport (Slc12a3)
Anatomy Link Frequency
embryos 1
Slc12a3 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 64 99.20 Very High Very High Very High
anesthesia 4 87.60 High High
cytokine 6 53.16 Quite High
Inflammation 12 52.76 Quite High
ketamine 2 44.32 Quite Low
vagus nerve 1 33.12 Quite Low
Inflammatory response 6 24.48 Low Low
Pyramidal cell 4 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurocysticercosis 46 100.00 Very High Very High Very High
Apoptosis 19 100.00 Very High Very High Very High
Central Nervous System Disease 56 99.20 Very High Very High Very High
Infection 62 94.96 High High
Cancer 2 79.24 Quite High
Cleft Palate 8 74.64 Quite High
Neurodegenerative Disease 2 68.92 Quite High
Parasitic Infection 2 68.48 Quite High
INFLAMMATION 18 52.76 Quite High
Neuroblastoma 2 50.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While it is likely that increased proliferation and decreased apoptosis in NCC of Spry1;Wnt1-Cre embryos contributes to the phenotype, it is also possible that similar to the Pdgfr?
Positive_regulation (increased) of NCC in embryos associated with apoptosis
1) Confidence 0.23 Published 2010 Journal BMC Dev Biol Section Body Doc Link PMC2874773 Disease Relevance 0.36 Pain Relevance 0
In the present study, we showed that TLRs 11–13 are expressed in the CNS and their expression was significantly upregulated during murine NCC.
Positive_regulation (upregulated) of NCC associated with central nervous system and neurocysticercosis
2) Confidence 0.14 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2631477 Disease Relevance 0.94 Pain Relevance 0.27
We harvested the larvae aseptically and induced murine NCC by intracranial injections of 50 ?
Positive_regulation (induced) of NCC associated with neurocysticercosis
3) Confidence 0.14 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2631477 Disease Relevance 0.77 Pain Relevance 0.19

General Comments

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