INT259861

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 13
Disease Relevance 2.69
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
lateral 1
band 1
limbs 1
Life1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 40 88.36 High High
medulla 18 70.84 Quite High
Spinal cord 57 70.24 Quite High
cerebral cortex 3 61.32 Quite High
Angina 20 51.12 Quite High
epidural 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Spinal Cord Injury 174 98.96 Very High Very High Very High
Coronary Heart Disease 20 98.20 Very High Very High Very High
Atherosclerosis 140 89.76 High High
Injury 24 87.56 High High
Calcification 40 74.60 Quite High
Atherosclerotic Plaque 30 68.48 Quite High
Cv General 3 Under Development 20 51.12 Quite High
Disease 10 43.04 Quite Low
Ataxia 3 25.28 Quite Low
Pathologic Constriction 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study showed that saving time of analysis by reducing the number of cross-sectional images used for volumetric data and thus analyzed (24 ± 11.5 vs. 12 ± 2.4 frames/cm) is offset by a significant but mild increase in measurement variability that is higher than the level of the intra-observer measurement variability.
Positive_regulation (increase) of variability
1) Confidence 0.01 Published 2010 Journal Int J Cardiovasc Imaging Section Body Doc Link PMC2868170 Disease Relevance 0.09 Pain Relevance 0.06
This may result in an increased variability of fibrous and fibro-lipidic tissue measurements (in the present study >5 and >11%, respectively).
Positive_regulation (increased) of variability
2) Confidence 0.01 Published 2010 Journal Int J Cardiovasc Imaging Section Body Doc Link PMC2868170 Disease Relevance 0.22 Pain Relevance 0.12
In RF–IVUS studies of mild-to-moderate coronary disease, analyzing less image frames saved analysis time, left most volumetric parameters greatly unaffected, and resulted in a no more than mild increase in measurement variability of volumetric data.



Positive_regulation (increase) of variability associated with coronary heart disease
3) Confidence 0.01 Published 2010 Journal Int J Cardiovasc Imaging Section Abstract Doc Link PMC2868170 Disease Relevance 0.16 Pain Relevance 0
Analyzing less cross-sectional image frames saved analysis time on the generation of volumetric RF–IVUS data in mild-to-moderate coronary disease, left most volumetric parameters greatly unaffected, and resulted in a no more than mild increase in measurement variability of volumetric data.



Positive_regulation (increase) of variability associated with coronary heart disease
4) Confidence 0.01 Published 2010 Journal Int J Cardiovasc Imaging Section Body Doc Link PMC2868170 Disease Relevance 0.29 Pain Relevance 0.05
As demonstrated in the current study, reduction of the number of image frames used for the generation of volumetric measurements is time sparing, but resulted in a mild increase in measurement variability for most geometrical and compositional volumetric RF–IVUS parameters; there were only for a few parameters (borderline) significant but mild differences versus measurements based on all frames.
Positive_regulation (increase) of variability
5) Confidence 0.01 Published 2010 Journal Int J Cardiovasc Imaging Section Body Doc Link PMC2868170 Disease Relevance 0.06 Pain Relevance 0
Between data obtained in Analysis I versus Analysis III, there was a mild increase in measurement variability for most geometrical and compositional volumetric RF–IVUS parameters when being compared to the intra-observer variability (Analysis I versus Analysis II).


Positive_regulation (increase) of variability
6) Confidence 0.01 Published 2010 Journal Int J Cardiovasc Imaging Section Body Doc Link PMC2868170 Disease Relevance 0 Pain Relevance 0
This increase in measurement variability appears to be the result of a somewhat more difficult image analysis (Analysis III, contour editing on a reduced number of image frames and less data), as the generation of volumes from 50% of the already contour-edited images of Analysis I (only less data) showed a lower measurement variability.
Positive_regulation (increase) of variability
7) Confidence 0.01 Published 2010 Journal Int J Cardiovasc Imaging Section Body Doc Link PMC2868170 Disease Relevance 0.14 Pain Relevance 0
Compared to the intra-observer variability, there was a mild increase in measurement variability for most geometrical and compositional volumetric RF–IVUS parameters.
Positive_regulation (increase) of variability
8) Confidence 0.01 Published 2010 Journal Int J Cardiovasc Imaging Section Abstract Doc Link PMC2868170 Disease Relevance 0.22 Pain Relevance 0
Potential mechanism of increased measurement variability
Positive_regulation (increased) of variability
9) Confidence 0.01 Published 2010 Journal Int J Cardiovasc Imaging Section Body Doc Link PMC2868170 Disease Relevance 0 Pain Relevance 0
Reduction in number of cross-sectional images for volumetric analysis could save analysis time but may also increase measurement variability of volumetric data.
Spec (may) Positive_regulation (increase) of variability
10) Confidence 0.01 Published 2010 Journal Int J Cardiovasc Imaging Section Abstract Doc Link PMC2868170 Disease Relevance 0.24 Pain Relevance 0
Therefore we also examined the effect of band support on the normal dogs, in case there was an effect to exacerbate the increased variability of weight support in the SCI dogs.
Positive_regulation (increased) of variability in band associated with spinal cord injury
11) Confidence 0.01 Published 2008 Journal BMC Vet Res Section Body Doc Link PMC2631515 Disease Relevance 0.56 Pain Relevance 0.04
Again, there were differences in this parameter between individual animals in both thoracic (0.13–0.79) and pelvic (0.16–1.02) limbs, including some notably much larger values than those calculated for normal individuals, implying an increased variability of foot placement.
Positive_regulation (increased) of variability in limbs
12) Confidence 0.01 Published 2008 Journal BMC Vet Res Section Body Doc Link PMC2631515 Disease Relevance 0.23 Pain Relevance 0
We show here that it is possible to quantify the increased variability in lateral support that results from thoracolumbar SCI and that this may recover independently of limb girdle coordination in the sagittal plane.
Positive_regulation (increased) of variability in lateral associated with spinal cord injury
13) Confidence 0.01 Published 2008 Journal BMC Vet Res Section Body Doc Link PMC2631515 Disease Relevance 0.47 Pain Relevance 0.07

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