INT260072

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.37
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.63
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (BRCA2, FANCC) cytoplasm (BRCA2, FANCC) nucleus (BRCA2, FANCC)
protein complex assembly (FANCC) DNA binding (BRCA2) protein complex (BRCA2)
Anatomy Link Frequency
stem cell 1
BRCA2 (Homo sapiens)
FANCC (Homo sapiens)
Pain Link Frequency Relevance Heat
Hsan 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 110 100.00 Very High Very High Very High
Cancer 52 64.88 Quite High
Skin Cancer 32 56.64 Quite High
Basal Cell Nevus Syndrome 10 26.56 Quite Low
Metastasis 4 14.92 Low Low
Disease 6 5.00 Very Low Very Low Very Low
Fanconi Anemia 4 5.00 Very Low Very Low Very Low
Pancreatic Cancer 4 5.00 Very Low Very Low Very Low
Freckles 4 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Significant association of FANCC-XPA methylation in group-A and FANCC-BRCA2 deletion in both age groups supported interlink between multiple DNA repair pathways.
BRCA2 Binding (association) of FANCC
1) Confidence 0.37 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2633285 Disease Relevance 0.48 Pain Relevance 0
Differential association of alterations in FANCC and PTCH1 with that of PHF2, XPA and two breast cancer susceptibility genes (BRCA1/BRCA2) in the two age groups suggests differences in their molecular pathogenesis and dysregulation of multiple DNA repair pathways as well as hedgehog dependent stem cell renewal pathway.



BRCA2 Binding (association) of FANCC in stem cell associated with breast cancer
2) Confidence 0.36 Published 2008 Journal Mol Cancer Section Abstract Doc Link PMC2633285 Disease Relevance 0.15 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox