INT260079

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Context Info
Confidence 0.62
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.55
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FANCC) nucleoplasm (FANCC) nucleus (FANCC)
protein complex assembly (FANCC) cytoplasm (FANCC)
Anatomy Link Frequency
MCF-7 1
FANCC (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 26 77.96 Quite High
Pain scale 3 74.72 Quite High
abdominal pain 26 57.20 Quite High
Hsan 2 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Pain score 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eczema 2 98.36 Very High Very High Very High
Vomiting 3 98.12 Very High Very High Very High
Hypersensitivity 2 97.68 Very High Very High Very High
Breast Cancer 110 97.56 Very High Very High Very High
Cancer 52 96.64 Very High Very High Very High
Asthma 2 95.32 Very High Very High Very High
Constipation 8 88.96 High High
Pain 26 77.96 Quite High
Abdominal Pain 29 57.20 Quite High
Rheumatoid Arthritis 2 49.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mRNA expression of PHF2, FANCC, PTCH1 and XPA in normal breast tissue (n = 6), and primary BC (n = 14) and 1 cell line (MCF-7) was analyzed by quantitative real-time (Q-PCR).
Spec (analyzed) Transcription (expression) of FANCC in MCF-7 associated with breast cancer
1) Confidence 0.62 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2633285 Disease Relevance 0.32 Pain Relevance 0
Q-PCR analysis of PHF2, FANCC and PTCH1 mRNA revealed reduced mRNA expression of in all these genes.
Transcription (expression) of FANCC
2) Confidence 0.48 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2633285 Disease Relevance 0.40 Pain Relevance 0
Medication prescription for FAC included one or more laxatives in 78 and anti-emetics in two cases; spasmolytics were never prescribed at all.
Transcription (prescription) of FAC associated with vomiting
3) Confidence 0.36 Published 2010 Journal Qual Life Res Section Body Doc Link PMC2836462 Disease Relevance 0.82 Pain Relevance 0.26

General Comments

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