INT260110

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Context Info
Confidence 0.48
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.50
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CD4) cell adhesion (CD4) plasma membrane (CD4)
enzyme binding (CD4)
Anatomy Link Frequency
regulatory T cells 2
T cells 2
CD4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 18 99.28 Very High Very High Very High
Inflammation 21 74.68 Quite High
methotrexate 3 45.04 Quite Low
corticosteroid 2 43.68 Quite Low
cytokine 18 5.00 Very Low Very Low Very Low
rheumatoid arthritis 9 5.00 Very Low Very Low Very Low
chemokine 9 5.00 Very Low Very Low Very Low
tolerance 8 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 48 100.00 Very High Very High Very High
Juvenile Chronic Polyarthritis 16 99.28 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 41 87.28 High High
Cold Sores 9 80.40 Quite High
INFLAMMATION 21 74.68 Quite High
Disease 16 53.20 Quite High
Rheumatic Diseases 12 50.00 Quite Low
Toxicity 3 48.56 Quite Low
Congenital Anomalies 2 13.16 Low Low
Autoimmune Disease 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, we find reduced levels of circulating CD4+CD25high regulatory T cells in polyarticular JIA (unpublished data).
Positive_regulation (circulating) of Regulation (regulatory T cells) of CD4 in regulatory T cells associated with arthritis
1) Confidence 0.48 Published 2008 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2633304 Disease Relevance 0.70 Pain Relevance 0.32
MIV-150 also prevented dendritic cell (DC)-facilitated infection of CD4+ T cells at nM concentrations [20].
Positive_regulation (facilitated) of Regulation (infection) of CD4 in T cells associated with infection
2) Confidence 0.19 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3016413 Disease Relevance 0.80 Pain Relevance 0

General Comments

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