INT260119

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.61
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CD4) cell adhesion (CD4) plasma membrane (CD4)
enzyme binding (CD4)
Anatomy Link Frequency
regulatory T cells 2
T cells 2
CD4 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 9 100.00 Very High Very High Very High
cytokine 27 94.40 High High
Arthritis 18 86.48 High High
chemokine 5 83.72 Quite High
Inflammation 21 83.00 Quite High
methotrexate 3 63.28 Quite High
tolerance 10 61.52 Quite High
corticosteroid 2 22.60 Low Low
Pain 2 5.00 Very Low Very Low Very Low
abatacept 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Influenza Virus Infection 70 100.00 Very High Very High Very High
Rheumatoid Arthritis 9 100.00 Very High Very High Very High
Juvenile Chronic Polyarthritis 16 86.48 High High
Sprains And Strains 11 85.60 High High
Immunization 16 83.04 Quite High
INFLAMMATION 21 83.00 Quite High
Anaerobic Bacterial Infections 14 67.68 Quite High
Systemic Lupus Erythematosus 13 66.08 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 36 58.60 Quite High
Disease 18 52.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CD4+CD25high regulatory T cells from RA subjects are capable of suppressing the production of IFN-?
Regulation (capable) of Localization (regulatory T cells) of CD4 in regulatory T cells associated with rheumatoid arthritis
1) Confidence 0.44 Published 2008 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2633304 Disease Relevance 0.81 Pain Relevance 0.41
Multiparametric flow cytometry assays were performed to determine the relative importance of the subpopulations of influenza-specific CD3+CD4+ and CD3+CD8+ T cells that produce IL-2, IFN-?
Spec (determine) Regulation (determine) of Spec (determine) Localization (importance) of CD4 in T cells associated with influenza virus infection
2) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2877091 Disease Relevance 0.81 Pain Relevance 0.05

General Comments

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