INT260210

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Context Info
Confidence 0.23
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.42
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (SEPT5) plasma membrane (SEPT5) cytoskeleton (SEPT5)
cell cycle (SEPT5) GTPase activity (SEPT5) cytoplasm (SEPT5)
Anatomy Link Frequency
T-cell 1
SEPT5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 1 74.48 Quite High
cytokine 20 16.84 Low Low
chemokine 3 9.84 Low Low
Inflammation 5 8.84 Low Low
Pain 4 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 43 98.04 Very High Very High Very High
Influenza Virus Infection 55 97.88 Very High Very High Very High
Immunization 36 97.12 Very High Very High Very High
Infection 17 88.52 High High
INFLAMMATION 6 8.84 Low Low
Hemolysis 16 5.00 Very Low Very Low Very Low
Fever 7 5.00 Very Low Very Low Very Low
Myalgia 5 5.00 Very Low Very Low Very Low
Influenza In Birds 5 5.00 Very Low Very Low Very Low
Contagious Ecthyma 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous clinical trials using other potential pandemic influenza strains such as H5N3 [2], [23]–[24] and H9N2 [25] have shown that the addition of MF59: i) significantly increases the immunogenicity of the H5 and H9 antigens, ii) confers cross-reactivity against antigenically drifted strains [17], [24], and iii) allows reduction of the antigen content.
Positive_regulation (increases) of H5 associated with influenza virus infection and sprains and strains
1) Confidence 0.23 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2634740 Disease Relevance 0.78 Pain Relevance 0
Besides for systemic cross-neutralizing antibodies, the induction of H5 specific mucosal IgA that was detected in some ferrets after the first immunization as well as the T-cell response may contribute to the protection of ferrets against a heterologous virus.
Positive_regulation (induction) of H5 in T-cell associated with immunization
2) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2694350 Disease Relevance 0.65 Pain Relevance 0.04

General Comments

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