INT260264

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Context Info
Confidence 0.26
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (MTOR, FKBP7) isomerase activity (FKBP7) mitochondrion (MTOR)
Golgi apparatus (MTOR) cytoplasm (MTOR) protein folding (FKBP7)
MTOR (Homo sapiens)
FKBP7 (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ovarian Cancer 63 99.96 Very High Very High Very High
Cancer 37 94.24 High High
Apoptosis 3 80.76 Quite High
Disease 8 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Abdominal Pain 1 5.00 Very Low Very Low Very Low
Residual Neoplasm 1 5.00 Very Low Very Low Very Low
Breast Cancer 1 5.00 Very Low Very Low Very Low
Recurrence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Apart from having prognostic impact our analysis also sheds light on previous unknown possible “druggable” targets in ovarian cancer; FKBP7, with the highest hazard ratio for individual genes in our study, appears to be especially of interest because FKBPs can be targeted with mTOR inhibitors [44].
mTOR Binding (targeted) of FKBP7 associated with ovarian cancer
1) Confidence 0.26 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2634794 Disease Relevance 0.87 Pain Relevance 0

General Comments

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