INT260267

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Context Info
Confidence 0.37
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.10
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (TFAM, TP53) DNA binding (TFAM, TP53) nucleus (TFAM, TP53)
cell differentiation (TP53) nucleoplasm (TP53) endoplasmic reticulum (TP53)
TFAM (Homo sapiens)
TP53 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 55.84 Quite High
alcohol 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 69 99.60 Very High Very High Very High
Apoptosis 7 98.92 Very High Very High Very High
Carcinoma 20 96.80 Very High Very High Very High
Targeted Disruption 1 92.96 High High
Endometroid Carcinoma 36 91.24 High High
Ovarian Cancer 63 87.08 High High
Skin Cancer 2 83.76 Quite High
Breast Cancer 1 54.12 Quite High
Endometrial Cancer 9 50.00 Quite Low
Malignant Neoplastic Disease 2 48.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Yoshida et al. suggested that the physical and functional interaction of p53 with mtTFA play an important role in apoptosis [10].
mtTFA Binding (interaction) of p53 associated with apoptosis
1) Confidence 0.37 Published 2010 Journal Virchows Arch Section Body Doc Link PMC2852529 Disease Relevance 1.44 Pain Relevance 0
Our transcription factor analysis demonstrated a positive prognostic impact for p53 as an “activated” transcription factor.
transcription factor Binding (impact) of p53
2) Confidence 0.01 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2634794 Disease Relevance 0.67 Pain Relevance 0.03

General Comments

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