INT260352

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Context Info
Confidence 0.50
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.34
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (NCF1) cytosol (NCF1) GTPase activity (NCF1)
cytoplasm (NCF1)
Anatomy Link Frequency
T cell 4
leukocyte 2
NCF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 96 96.36 Very High Very High Very High
Arthritis 15 87.00 High High
Neuritis 3 77.40 Quite High
Demyelination 3 34.60 Quite Low
Crohn's disease 3 22.20 Low Low
Inflammation 3 15.64 Low Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neutrophil Disorders 15 98.22 Very High Very High Very High
Demyelinating Disease 102 96.36 Very High Very High Very High
Malaria 72 92.68 High High
Disease 69 90.00 High High
Targeted Disruption 3 89.08 High High
Arthritis 15 87.00 High High
Multiple Sclerosis 9 79.68 Quite High
Experimental Autoimmune Neuritis 3 77.40 Quite High
Autoimmune Disease 39 74.40 Quite High
Parasitic Infection 9 58.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unlike the heterogeneous CGD-causing mutations in other leukocyte NADPH oxidase subunits, about 95% of the cases are attributed to a NCF1 mutation carry a common dinucleotide deletion (?
Positive_regulation (attributed) of Gene_expression (mutation) of NCF1 in leukocyte associated with neutrophil disorders
1) Confidence 0.50 Published 2008 Journal Malar J Section Body Doc Link PMC2635379 Disease Relevance 1.36 Pain Relevance 0.23
1:1 could lead to enhanced expression of NCF1 and subsequently to higher ROI production which could in turn modulate T cell responses.
Positive_regulation (enhanced) of Gene_expression (expression) of NCF1 in T cell
2) Confidence 0.50 Published 2008 Journal Malar J Section Body Doc Link PMC2635379 Disease Relevance 0.96 Pain Relevance 0.22
1:1 could lead to enhanced expression of NCF1 and subsequently to higher ROI production which could in turn modulate T cell responses.
Positive_regulation (lead) of Gene_expression (expression) of NCF1 in T cell
3) Confidence 0.50 Published 2008 Journal Malar J Section Body Doc Link PMC2635379 Disease Relevance 1.01 Pain Relevance 0.24

General Comments

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