INT260380

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.46
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (IGLL1)
Anatomy Link Frequency
B cells 2
lymphocytes 2
IGLL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 22 50.00 Quite Low
cva 6 25.80 Quite Low
headache 4 20.20 Low Low
methotrexate 5 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Influenza Virus Infection 33 97.84 Very High Very High Very High
Toxicity 42 97.04 Very High Very High Very High
Apoptosis 12 95.80 Very High Very High Very High
Chromosome Aberrations 6 95.36 Very High Very High Very High
Necrosis 12 88.20 High High
Cancer 26 86.56 High High
Disease 11 83.32 Quite High
Poisoning 6 74.08 Quite High
Immunization 11 51.04 Quite High
Rheumatoid Arthritis 22 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The number of B cells producing Pneumo23-specific switched Ig was lower (but not significant) as compared with the influenza-specific B cells.
Negative_regulation (switched) of Gene_expression (producing) of Ig in B cells associated with influenza virus infection
1) Confidence 0.02 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911904 Disease Relevance 0.52 Pain Relevance 0
In a study of cultured human lymphocytes, increased Ig production was observed in cells exposed to lower levels of TCs (T-2, DAS, DON, NIV), whereas decreased Ig production was reported at higher levels [77].
Negative_regulation (decreased) of Gene_expression (production) of Ig in lymphocytes
2) Confidence 0.00 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635619 Disease Relevance 0.23 Pain Relevance 0
NIV inhibits Ig production in mice [103].
Negative_regulation (inhibits) of Gene_expression (production) of Ig
3) Confidence 0.00 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635619 Disease Relevance 0.71 Pain Relevance 0

General Comments

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