INT260399

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Context Info
Confidence 0.19
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.40
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Sod3) response to stress (Sod3) cytoplasm (Sod3)
cytosol (Sod3) extracellular space (Sod3) extracellular region (Sod3)
Sod3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 4 94.48 High High
Inflammation 4 91.92 High High
ischemia 2 79.88 Quite High
medulla 2 58.68 Quite High
potassium channel 4 34.52 Quite Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 28 98.60 Very High Very High Very High
Hypertension 72 92.20 High High
INFLAMMATION 4 91.92 High High
Apoptosis 28 90.16 High High
Cardiovascular Disease 4 87.80 High High
Hyperglycemia 6 83.44 Quite High
Diabetes Mellitus 128 80.20 Quite High
Cv Unclassified Under Development 2 79.88 Quite High
Increased Venous Pressure Under Development 6 78.36 Quite High
Toxicity 2 70.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
generation, which may be due to a decrease in the levels of NADPH oxidase [24], a heme-dependent protein, and/or an increase in the levels of EC-SOD [25].
Positive_regulation (increase) of EC-SOD
1) Confidence 0.19 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635644 Disease Relevance 0.75 Pain Relevance 0.05
The mechanism by which HO-1 is involved in increased adiponectin levels is related to the function of HO-1 as a stress response/chaperone protein as well as its ability to decrease ROS by increasing glutathione and EC-SOD levels [5, 15, 25] and by decreasing O2?
Positive_regulation (increasing) of EC-SOD associated with stress
2) Confidence 0.12 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635644 Disease Relevance 0.65 Pain Relevance 0.20

General Comments

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