INT260439

Context Info Confidence 0.01 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.08 Pain Relevance 0.07

extracellular space (Il6) extracellular region (Il6)

Anatomy Link Frequency plasma 2 IFNA1 (Homo sapiens) Il6 (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 28 87.12 Inflammation 8 61.68 Pain 1 36.48 agonist 12 5.00 Central nervous system 2 5.00 chemokine 2 5.00 Potency 2 5.00 sodium channel 1 5.00 anesthesia 1 5.00 Inflammatory mediators 1 5.00

Disease Link Frequency Relevance Heat Toxicity 11 97.08 Weight Loss 4 92.16 Influenza Virus Infection 92 90.52 Infection 35 87.92 Septic Shock 1 64.84 Arthritis 2 61.68 Coronary Heart Disease 1 60.64 Experimental Autoimmune Encephalomyelitis 1 59.24 Autoimmune Disease 3 57.36 Hepatitis 4 51.04

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

CpG ODN encapsulated within stabilized antisense-lipid particles increased plasma concentrations of IL-6, -12, IFN-?

Positive_regulation (increased) of IFN Binding (concentrations) of IL-6 in plasma

1) Confidence 0.01 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635754 Disease Relevance 1.08 Pain Relevance 0.07

General Comments

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