INT260478

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Context Info
Confidence 0.30
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.23
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hif1a) signal transduction (Hif1a) nucleolus (Hif1a)
nucleus (Hif1a) protein binding transcription factor activity (Hif1a) DNA binding (Hif1a)
Hif1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
allodynia 1 65.44 Quite High
Nerve growth factor 1 52.24 Quite High
nMDA receptor 9 50.00 Quite Low
isoflurane 6 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
Glutamate receptor 4 5.00 Very Low Very Low Very Low
potassium channel 3 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 183 100.00 Very High Very High Very High
Adhesions 3 99.14 Very High Very High Very High
Neuropathic Pain 1 65.44 Quite High
Ganglion Cysts 9 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low
Diabetic Retinopathy 4 5.00 Very Low Very Low Very Low
Retinal Diseases 3 5.00 Very Low Very Low Very Low
Decapitation 3 5.00 Very Low Very Low Very Low
Diabetes Mellitus 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of a few retinal mRNAs known to be induced by hypoxia, including HIF-1?
Negative_regulation (known) of Positive_regulation (induced) of HIF-1 associated with hypoxia
1) Confidence 0.30 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2635851 Disease Relevance 0.87 Pain Relevance 0
Previous studies have confirmed a link between hypoxia and the formation of focal adhesions (Seko et al. 1999), but we were unable to detect the simultaneous upregulation of HIF-1?
Neg (unable) Negative_regulation (detect) of Positive_regulation (upregulation) of HIF-1 associated with hypoxia and adhesions
2) Confidence 0.03 Published 2010 Journal J Mol Neurosci Section Body Doc Link PMC2825316 Disease Relevance 0.36 Pain Relevance 0.09

General Comments

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