INT260518

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Context Info
Confidence 0.13
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Prnp, Gopc) plasma membrane (Prnp, Gopc) cytoplasm (Prnp, Gopc)
transport (Gopc) endoplasmic reticulum (Prnp) nucleolus (Prnp)
Anatomy Link Frequency
brain 2
Prnp (Mus musculus)
Gopc (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 5 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 42 98.80 Very High Very High Very High
Drug Induced Neurotoxicity 1 92.76 High High
Creutzfeldt Jakob Disease 9 85.76 High High
Sprains And Strains 69 69.20 Quite High
Congenital Anomalies 7 58.88 Quite High
Tremor 5 56.88 Quite High
Disease 76 50.00 Quite Low
Attention Deficit Hyperactivity Disorder 2 46.80 Quite Low
Aggression 2 45.36 Quite Low
Death 3 33.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We tagged the murine prion protein by introducing a human myc epitope tag (EQKLISEEDL) at its C terminus next to Ser230 and amino proximally to the C-terminal signal sequence for the GPI anchor (Fig. 1A).
prion protein Binding (introducing) of Fig
1) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2635968 Disease Relevance 0.35 Pain Relevance 0
None of these conditions resulted in detectable de novo formation of PrPSc in healthy brain homogenate from hamsters (Fig.
PrPSc Binding (formation) of Fig in brain
2) Confidence 0.05 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2675078 Disease Relevance 0.35 Pain Relevance 0
None of these conditions resulted in detectable de novo formation of PrPSc in healthy brain homogenate from hamsters (Fig.
PrPSc Binding (formation) of Fig in brain
3) Confidence 0.05 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2675078 Disease Relevance 0.35 Pain Relevance 0

General Comments

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