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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.06
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mapk14, Sp1) nucleus (Mapk14, Sp1) mitochondrion (Mapk14)
cell morphogenesis (Mapk14) intracellular (Sp1) DNA binding (Sp1)
Mapk14 (Rattus norvegicus)
Sp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 3 89.52 High High
cytokine 11 83.92 Quite High
Inflammation 38 82.00 Quite High
Inflammatory response 16 46.16 Quite Low
metalloproteinase 4 37.92 Quite Low
chemokine 4 25.40 Quite Low
Bile 53 5.00 Very Low Very Low Very Low
fibrosis 14 5.00 Very Low Very Low Very Low
ischemia 11 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 11 99.30 Very High Very High Very High
INFLAMMATION 53 89.52 High High
Cholestasis 33 82.08 Quite High
Obstructive Jaundice 5 78.20 Quite High
Infection 4 75.92 Quite High
Cirrhosis 24 65.48 Quite High
Bacterial Infection 1 59.24 Quite High
Pressure And Volume Under Development 5 50.80 Quite High
Jaundice 3 50.32 Quite High
Injury 18 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the presence of extrahepatic biliary obstruction, the activation of p38, c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) considered 'stress kinases' [108] would be produced. p38 MAP kinase in particular has been suggested to regulate IL10 synthesis through activation of Sp1 transcription factor rather than through the NF?
p38 MAP kinase Regulation (regulate) of Positive_regulation (activation) of Sp1 transcription factor associated with stress
1) Confidence 0.01 Published 2008 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2637833 Disease Relevance 1.06 Pain Relevance 0.25

General Comments

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