INT260745

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Mapk1, Mapk1) mitochondrion (Mapk1, Mapk1) protein complex (Mapk1, Mapk1)
cytoplasm (Mapk1, Mapk1) cytosol (Mapk1, Mapk1) signal transduction (Mapk1, Mapk1)
Mapk1 (Mus musculus)
Mapk1 (Mus musculus)
Pain Term Frequency Confidence Heat
Inflammation 38 88.00 High High
Inflammatory mediators 3 84.56 Quite High
cytokine 11 78.96 Quite High
metalloproteinase 4 43.92 Quite Low
Inflammatory response 16 41.20 Quite Low
chemokine 4 31.40 Quite Low
Enkephalin 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Mechanotransduction 1 5.00 Very Low Very Low Very Low
Serotonin 1 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Stress 11 100.00 Very High Very High Very High
INFLAMMATION 53 88.00 High High
Obstructive Jaundice 5 84.20 Quite High
Cholestasis 33 77.12 Quite High
Infection 4 76.16 Quite High
Cirrhosis 24 71.48 Quite High
Bacterial Infection 1 65.24 Quite High
Pressure And Volume Under Development 5 56.80 Quite High
Injury 18 50.00 Quite Low
Jaundice 3 45.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the presence of extrahepatic biliary obstruction, the activation of p38, c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) considered 'stress kinases' [108] would be produced. p38 MAP kinase in particular has been suggested to regulate IL10 synthesis through activation of Sp1 transcription factor rather than through the NF?
extracellular signal-regulated kinase Regulation (regulate) of Positive_regulation (activation) of ERK associated with stress
1) Confidence 0.02 Published 2008 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2637833 Disease Relevance 1.03 Pain Relevance 0.25

General Comments

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