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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TLR4, Ecm1) intracellular (TLR4) enzyme binding (Ecm1)
signal transducer activity (Ecm1) cytoplasm (TLR4) extracellular space (Ecm1)
TLR4 (Homo sapiens)
Ecm1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 38 100.00 Very High Very High Very High
cytokine 11 87.20 High High
chemokine 4 83.20 Quite High
metalloproteinase 4 79.60 Quite High
ischemia 11 38.64 Quite Low
fibrosis 14 27.48 Quite Low
Mechanotransduction 1 14.00 Low Low
Bile 53 11.40 Low Low
Inflammatory response 16 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 53 100.00 Very High Very High Very High
Injury 18 86.92 High High
Hypersensitivity 1 56.56 Quite High
Cholestasis 33 50.00 Quite Low
Cirrhosis 24 41.60 Quite Low
Cv Unclassified Under Development 11 38.64 Quite Low
Liver Disease 4 38.56 Quite Low
Reperfusion Injury 2 37.92 Quite Low
Fibrosis 10 27.48 Quite Low
Adhesions 3 20.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fragments of ECM proteins and hyaluronan have the ability to promote inflammation by binding Toll-like receptors (TLR)-4 and TLR-2 [81], by activating the transcriptional regulatory complex of nuclear factor (NF)?
Toll Binding (binding) of ECM associated with inflammation
1) Confidence 0.02 Published 2008 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2637833 Disease Relevance 0.44 Pain Relevance 0.38

General Comments

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