INT260833

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.61
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (NRP2, Flt1) plasma membrane (NRP2, Flt1) endosome (Flt1)
Golgi apparatus (Flt1) cell adhesion (NRP2) nucleus (Flt1)
NRP2 (Homo sapiens)
Flt1 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 171 99.96 Very High Very High Very High
Osteoarthritis 9 89.84 High High
Inflammation 69 88.68 High High
cytokine 6 82.76 Quite High
Arthritis 24 50.00 Quite Low
chemokine 6 20.28 Low Low
antagonist 15 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
abatacept 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibromyalgia 3 100.00 Very High Very High Very High
Rheumatoid Arthritis 174 99.96 Very High Very High Very High
Hyperplasia 18 92.84 High High
Osteoarthritis 9 89.84 High High
INFLAMMATION 78 88.68 High High
Apoptosis 12 83.20 Quite High
Disease 30 74.48 Quite High
Starvation 3 63.20 Quite High
Cancer 30 54.16 Quite High
Ocular Toxicity (including Many Sub-types) 3 45.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Second, via interaction with Flt-1, VEGF165 may directly stimulate the productions of cytochemokines, such as TNF-?
VEGF165 Binding (interaction) of Flt-1
1) Confidence 0.00 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2638142 Disease Relevance 1.30 Pain Relevance 0.53
VEGF165 exerts its biological effects by binding with its receptor subtypes, that is, fms-like tyrosine kinase (Flt-1), kinase insert domain-containing receptor (KDR) and neuropilin-1 (NP-1) [3].
VEGF165 Binding (binding) of fms-like tyrosine kinase associated with fibromyalgia
2) Confidence 0.00 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2638142 Disease Relevance 1.15 Pain Relevance 0.35
VEGF165 exerts its biological effects by binding with its receptor subtypes, that is, fms-like tyrosine kinase (Flt-1), kinase insert domain-containing receptor (KDR) and neuropilin-1 (NP-1) [3].
VEGF165 Binding (binding) of Flt-1 associated with fibromyalgia
3) Confidence 0.00 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2638142 Disease Relevance 1.15 Pain Relevance 0.35

General Comments

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