INT260874

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.17
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SNRNP70) mRNA processing (SNRNP70) RNA binding (SNRNP70)
nucleus (SNRNP70)
SNRNP70 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 120 100.00 Very High Very High Very High
Arthritis 164 92.88 High High
Multiple sclerosis 54 82.72 Quite High
Neuropeptide 6 50.00 Quite Low
Inflammation 19 5.00 Very Low Very Low Very Low
Crohn's disease 4 5.00 Very Low Very Low Very Low
spinal inflammation 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 131 100.00 Very High Very High Very High
Juvenile Chronic Polyarthritis 144 92.88 High High
Mental Disorders 1 91.84 High High
Disease 93 91.28 High High
Demyelinating Disease 60 82.72 Quite High
Disease Susceptibility 4 50.00 Quite Low
Inflammatory Bowel Disease 9 45.56 Quite Low
Asthma 6 45.24 Quite Low
Autoimmune Disease 26 5.00 Very Low Very Low Very Low
INFLAMMATION 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the final analysis (employing a total of 12 360 individuals), association with rs6897932 (the IL7R associated SNP) was confirmed and significant association was also established with rs12722489 (P = 3.0 × 10?
Positive_regulation (confirmed) of SNP Binding (association) of
1) Confidence 0.49 Published 2008 Journal Brain Section Body Doc Link PMC2639203 Disease Relevance 0.43 Pain Relevance 0.17
Among these, the association of the SNP rs10263447 remained significant after Bonferroni correction when a dominant model was tested on the entire sample [p?
Positive_regulation (significant) of SNP Binding (association) of
2) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2825264 Disease Relevance 0.60 Pain Relevance 0.17
Association of this SNP with RA was also reported in the meta-analysis of two published GWAS.20

Genotyping

Positive_regulation (reported) of SNP Binding (Association) of associated with rheumatoid arthritis
3) Confidence 0.09 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2935325 Disease Relevance 0.58 Pain Relevance 0.29
Association of this SNP with RA was also reported in the meta-analysis of two published GWAS.20
Positive_regulation (reported) of SNP Binding (Association) of associated with rheumatoid arthritis
4) Confidence 0.09 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2935325 Disease Relevance 0.56 Pain Relevance 0.28

General Comments

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