INT260877

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 4.28
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (HEPACAM) cell cycle (HEPACAM) cytoplasm (HEPACAM)
Anatomy Link Frequency
stomach 1
HEPACAM (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 2 77.28 Quite High
Multiple sclerosis 100 50.00 Quite Low
alcohol 1 40.48 Quite Low
cryotherapy 14 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Chronic pancreatitis 4 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 425 100.00 Very High Very High Very High
Stomach Cancer 10 99.84 Very High Very High Very High
Disease 168 99.52 Very High Very High Very High
Breast Cancer 162 99.40 Very High Very High Very High
Spinal Tumor 2 93.44 High High
Glioblastoma 10 92.32 High High
Malignant Neoplastic Disease 3 89.44 High High
Anaplastic Astrocytoma 2 88.00 High High
Hepatocellular Cancer 10 87.24 High High
Prostate Cancer 111 84.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A set of 11 miRNAs are reported in the cancer-miRNA network that are dysregulated in stomach tumor tissue among which 10 are significantly upregulated.


Regulation (dysregulated) of cancer-miRNA in stomach associated with cancer and stomach cancer
1) Confidence 0.03 Published 2010 Journal Silenc Section Body Doc Link PMC2835996 Disease Relevance 2.21 Pain Relevance 0.04
One factor that has been shown to improve both the cancer control and functional results of radical prostatectomy is the experience of the surgeon, regardless of the technique.39


Regulation (control) of cancer associated with cancer
2) Confidence 0.03 Published 2010 Journal Clin Interv Aging Section Body Doc Link PMC2920199 Disease Relevance 0.48 Pain Relevance 0
The cancer-miRNA network is visualized by publicly available tool Pajek
Regulation (visualized) of cancer-miRNA associated with cancer
3) Confidence 0.02 Published 2010 Journal Silenc Section Body Doc Link PMC2835996 Disease Relevance 0.56 Pain Relevance 0
Breast cancer has a complex etiology where susceptibility is influenced by both environmental and genetic factors.
Regulation (influenced) of susceptibility associated with breast cancer
4) Confidence 0.01 Published 2010 Journal Current Genomics Section Body Doc Link PMC2878980 Disease Relevance 0.92 Pain Relevance 0
One of the most notable features of the GWAS completed to date is the consistent observation that association tests are modestly inflated at neutral markers (i.e. those that do not influence susceptibility) in comparison with what would be expected if sampling error were the only source of variance.
Neg (not) Regulation (influence) of susceptibility
5) Confidence 0.00 Published 2008 Journal Brain Section Body Doc Link PMC2639203 Disease Relevance 0 Pain Relevance 0
Direct GWAS remain beyond affordable and practical technologies at this time but indirect GWAS are possible and have proven to be a highly successful means to identify common variants influencing susceptibility to complex disease (Duerr et al., 2006; Easton et al., 2007; Gudmundsson et al., 2007; Hampe et al., 2007; Helgadottir et al., 2007; Hunter et al., 2007; Libioulle et al., 2007; McPherson et al., 2007; Rioux et al., 2007; Saxena et al., 2007; Scott et al., 2007; Sladek et al., 2007; Stacey et al., 2007; Steinthorsdottir et al., 2007; WTCCC, 2007; Yeager et al., 2007).
Regulation (influencing) of susceptibility associated with disease
6) Confidence 0.00 Published 2008 Journal Brain Section Body Doc Link PMC2639203 Disease Relevance 0.10 Pain Relevance 0

General Comments

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