INT260878

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Context Info
Confidence 0.33
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.87
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL7R) extracellular region (IL7R) cell morphogenesis (IL7R)
plasma membrane (IL7R)
IL7R (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 150 98.60 Very High Very High Very High
Inflammation 6 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Demyelination 3 5.00 Very Low Very Low Very Low
Neuritis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 168 98.60 Very High Very High Very High
Mental Disorders 3 91.84 High High
Disease 135 76.24 Quite High
Recurrence 18 5.00 Very Low Very Low Very Low
Autoimmune Disease 9 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Neuromyelitis Optica 3 5.00 Very Low Very Low Very Low
Optic Atrophy 3 5.00 Very Low Very Low Very Low
Optic Neuritis 3 5.00 Very Low Very Low Very Low
Optic Disorders 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the final analysis (employing a total of 12 360 individuals), association with rs6897932 (the IL7R associated SNP) was confirmed and significant association was also established with rs12722489 (P = 3.0 × 10?
IL7R Binding (association) of
1) Confidence 0.33 Published 2008 Journal Brain Section Body Doc Link PMC2639203 Disease Relevance 0.43 Pain Relevance 0.17
Following on from their analysis of genomic convergence Gregory et al. (2007) established significant association with the IL7R SNP rs6897932 (P = 2.9 × 10?
IL7R Binding (association) of
2) Confidence 0.33 Published 2008 Journal Brain Section Body Doc Link PMC2639203 Disease Relevance 0.20 Pain Relevance 0.10
Taking the IL7R association as an example we can see that the multiple sclerosis associated allele of rs6897932 has a frequency of 72% which means that ?
IL7R Binding (association) of associated with multiple sclerosis
3) Confidence 0.25 Published 2008 Journal Brain Section Body Doc Link PMC2639203 Disease Relevance 0.24 Pain Relevance 0.08

General Comments

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