INT260894

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.36
Pain Relevance 0.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CRH, MMP3) extracellular region (CRH, MMP3) peptidase activity (MMP3)
signal transduction (CRH) proteinaceous extracellular matrix (MMP3) nucleus (MMP3)
Anatomy Link Frequency
fibroblasts 4
CRH (Homo sapiens)
MMP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 196 100.00 Very High Very High Very High
Inflammation 6 88.96 High High
cytokine 12 83.52 Quite High
Dismenorea 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 6 88.96 High High
Premature Birth 12 75.16 Quite High
Pre-term Labor 14 67.84 Quite High
Rupture 2 48.80 Quite Low
Emergencies 2 27.68 Quite Low
Asphyxia 2 19.36 Low Low
Dysmenorrhea 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Abruptio Placentae 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, our present aim was to determine if CRH has an effect on the secretion of IL-8, MMP-1 and MMP-3 in both preterm and term cervical fibroblasts.
CRH Regulation (effect) of Localization (secretion) of MMP-3 in fibroblasts associated with metalloproteinase
1) Confidence 0.21 Published 2008 Journal Molecular Human Reproduction Section Body Doc Link PMC2639405 Disease Relevance 0.27 Pain Relevance 0.36
We have shown that CRH increased the secretion of IL-8 in both preterm and term cervical fibroblasts, but did not affect the secretion of MMP-1 and MMP-3.
CRH Neg (not) Regulation (affect) of Localization (secretion) of MMP-3 in fibroblasts associated with metalloproteinase
2) Confidence 0.21 Published 2008 Journal Molecular Human Reproduction Section Body Doc Link PMC2639405 Disease Relevance 0.09 Pain Relevance 0.49

General Comments

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