INT260895

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Context Info
Confidence 0.11
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 0.31
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CRH, MMP1) peptidase activity (MMP1) signal transduction (CRH)
extracellular space (CRH) proteinaceous extracellular matrix (MMP1) response to stress (CRH)
Anatomy Link Frequency
fibroblasts 2
CRH (Homo sapiens)
MMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 196 100.00 Very High Very High Very High
Inflammation 6 58.84 Quite High
cytokine 12 5.00 Very Low Very Low Very Low
Dismenorea 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pre-term Labor 14 94.60 High High
INFLAMMATION 6 58.84 Quite High
Premature Birth 12 5.00 Very Low Very Low Very Low
Dysmenorrhea 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Asphyxia 2 5.00 Very Low Very Low Very Low
Emergencies 2 5.00 Very Low Very Low Very Low
Abruptio Placentae 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Breech Presentation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Different secretion patterns of matrix metalloproteinases and IL-8 and effect of corticotropin-releasing hormone in preterm and term cervical fibroblasts

The aims of the present study were to compare the levels of mRNA and protein expression of matrix metalloproteinase (MMP)-1, -3, -8 and -9 in human cervical tissue in preterm and term labor as well as not in labor and to determine if corticotropin-releasing hormone (CRH) has an effect on MMP-1, -3 and interleukin (IL)-8 secretion in both preterm and term cervical fibroblasts.

CRH Regulation (effect) of MMP-1 in fibroblasts associated with metalloproteinase
1) Confidence 0.11 Published 2008 Journal Molecular Human Reproduction Section Title Doc Link PMC2639405 Disease Relevance 0.15 Pain Relevance 0.37
Different secretion patterns of matrix metalloproteinases and IL-8 and effect of corticotropin-releasing hormone in preterm and term cervical fibroblasts

The aims of the present study were to compare the levels of mRNA and protein expression of matrix metalloproteinase (MMP)-1, -3, -8 and -9 in human cervical tissue in preterm and term labor as well as not in labor and to determine if corticotropin-releasing hormone (CRH) has an effect on MMP-1, -3 and interleukin (IL)-8 secretion in both preterm and term cervical fibroblasts.

corticotropin-releasing hormone Regulation (effect) of MMP-1 in fibroblasts associated with metalloproteinase
2) Confidence 0.11 Published 2008 Journal Molecular Human Reproduction Section Title Doc Link PMC2639405 Disease Relevance 0.15 Pain Relevance 0.37

General Comments

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