INT260908

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.53
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (Smarca4) helicase activity (Smarca4) extracellular matrix organization (Smarca4)
DNA binding (Smarca4) nucleolus (Smarca4) nucleus (Smarca4)
Smarca4 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 4 69.12 Quite High
addiction 4 25.52 Quite Low
Eae 7 5.00 Very Low Very Low Very Low
Dopamine 5 5.00 Very Low Very Low Very Low
Nucleus accumbens 5 5.00 Very Low Very Low Very Low
Hippocampus 5 5.00 Very Low Very Low Very Low
antidepressant 4 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
amygdala 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 34 93.12 High High
Anxiety Disorder 12 85.24 High High
Drug Dependence 4 25.92 Quite Low
Apoptosis 9 16.88 Low Low
Stress 14 5.00 Very Low Very Low Very Low
Convulsion 10 5.00 Very Low Very Low Very Low
Epilepsy 6 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Repression 3 5.00 Very Low Very Low Very Low
Depression 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, heterozygous females are able to accumulate maternal transcripts of BRG1 which may support development and survival to the blastocyst stage.
Positive_regulation (accumulate) of BRG1
1) Confidence 0.21 Published 2008 Journal Molecular Human Reproduction Section Body Doc Link PMC2639449 Disease Relevance 0.22 Pain Relevance 0
Taken together, the data show that both manipulations, the increase in the amount of transcription activator (CREB) or removal of transcription suppressor (ICER), change behavior in the same direction (i.e., enhance long-term memory).
Positive_regulation (increase) of transcription activator
2) Confidence 0.02 Published 2009 Journal Mol Neurobiol Section Body Doc Link PMC2699388 Disease Relevance 0.31 Pain Relevance 0.03

General Comments

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