INT260911

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Context Info
Confidence 0.30
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Zfp36) mRNA binding (Zfp36) nucleus (Zfp36)
DNA binding (Zfp36) response to stress (Zfp36) cytoplasm (Zfp36)
Zfp36 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 1 77.28 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 3 94.72 High High
Arthritis 1 77.28 Quite High
Targeted Disruption 10 60.64 Quite High
Male Infertility 2 17.52 Low Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Reprotox - General 3 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Embryonic Lethality 1 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies have indicated that ZFP36 phosphorylation is regulated by p38 MAPK signalling and that phosphorylated ZFP36 displays reduced RNA-binding activity associated with reduced target mRNA degradation (Fechir et al., 2005; Song et al., 2005; Marderosian et al., 2006).
Regulation (regulated) of Phosphorylation (phosphorylation) of ZFP36
1) Confidence 0.30 Published 2008 Journal Molecular Human Reproduction Section Body Doc Link PMC2639449 Disease Relevance 0.23 Pain Relevance 0.04

General Comments

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