INT260913

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Context Info
Confidence 0.18
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (Smarca4) helicase activity (Smarca4) extracellular matrix organization (Smarca4)
DNA binding (Smarca4) nucleolus (Smarca4) nucleus (Smarca4)
Anatomy Link Frequency
embryos 2
Smarca4 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 4 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 20 93.04 High High
Congenital Anomalies 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Male Infertility 4 5.00 Very Low Very Low Very Low
Reprotox - General 3 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Embryonic Lethality 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, 78% of the maternally depleted BRG1 embryos arrest at the 2-cell stage compared with only 3% of control embryos (Bultman et al., 2006).
Negative_regulation (depleted) of BRG1 in embryos
1) Confidence 0.18 Published 2008 Journal Molecular Human Reproduction Section Body Doc Link PMC2639449 Disease Relevance 0.15 Pain Relevance 0
Transcription was also reduced in BRG1 maternally depleted embryos by up to 30% (Bultman et al., 2006).
Negative_regulation (reduced) of BRG1 in embryos
2) Confidence 0.18 Published 2008 Journal Molecular Human Reproduction Section Body Doc Link PMC2639449 Disease Relevance 0.14 Pain Relevance 0

General Comments

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