INT260945

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mapk14, Aqp3) transport (Aqp3) mitochondrion (Mapk14)
cell morphogenesis (Mapk14) transmembrane transport (Aqp3) response to stress (Mapk14)
Mapk14 (Mus musculus)
Aqp3 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 1 63.32 Quite High
cytokine 2 61.88 Quite High
COX2 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 3 98.08 Very High Very High Very High
INFLAMMATION 2 63.08 Quite High
Targeted Disruption 10 52.16 Quite High
Reprotox - General 3 2 14.72 Low Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Male Infertility 2 5.00 Very Low Very Low Very Low
Embryonic Lethality 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have also used a similar approach to discover that p38 MAPK increases AQP 3 and 9 expression (mRNA and protein) in response to hyperosmotic stress, but only when the medium is made hyperosmotic with sucrose and not with glycerol (Bell and Watson, unpublished results).
p38 MAPK Positive_regulation (increases) of Gene_expression (expression) of AQP 3 associated with stress
1) Confidence 0.29 Published 2008 Journal Molecular Human Reproduction Section Body Doc Link PMC2639449 Disease Relevance 0.21 Pain Relevance 0.09

General Comments

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