INT261008

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Context Info
Confidence 0.29
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.64
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Gmcl1)
Gmcl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 10 5.00 Very Low Very Low Very Low
ischemia 8 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 160 99.24 Very High Very High Very High
Stress 36 97.88 Very High Very High Very High
Critical Illness 12 94.72 High High
Disease 8 94.28 High High
Colitis 2 80.24 Quite High
Sprains And Strains 16 76.32 Quite High
Inflammatory Bowel Disease 4 68.56 Quite High
Pouchitis 2 67.92 Quite High
Injury 6 40.84 Quite Low
Apoptosis 36 39.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Two factors directly associate with mucosal GSH: dietary GSH levels [35] and GSH biosynthesis, of which the latter is in turn dependent on cysteine availability and GCL activity [36].
Regulation (dependent) of GCL
1) Confidence 0.29 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2639703 Disease Relevance 0.29 Pain Relevance 0
However, as the probiotics used in the current study showed severe adverse effects in intensive care AP patients [24], and since the present effects on GCL activity most likely resulted from a mild oxidative stress, this combination of probiotics is not a defendable treatment option in critically ill patients.
Regulation (effects) of GCL associated with stress, critical illness and pancreatitis
2) Confidence 0.17 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2639703 Disease Relevance 1.35 Pain Relevance 0

General Comments

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