INT261013

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.25
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Cldn2) plasma membrane (Cldn2)
Anatomy Link Frequency
epithelial cell 1
Cldn2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 5 90.84 High High
imagery 2 86.88 High High
ischemia 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 18 98.12 Very High Very High Very High
Pancreatitis 80 96.62 Very High Very High Very High
Stress 18 62.12 Quite High
Sprains And Strains 8 5.00 Very Low Very Low Very Low
Critical Illness 6 5.00 Very Low Very Low Very Low
Systemic Inflammatory Response Syndrome 5 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AP-induced barrier dysfunction was characterized by epithelial cell apoptosis and alterations of tight junction proteins (i.e. disruption of occludin and claudin-1 and up-regulation of claudin-2) and correlated with lipid peroxidation (r>0.8).
Positive_regulation (regulation) of claudin-2 in epithelial cell associated with pancreatitis and apoptosis
1) Confidence 0.07 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2639703 Disease Relevance 1.25 Pain Relevance 0.11

General Comments

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