INT261017

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Context Info
Confidence 0.22
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.88
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gclc) ligase activity (Gclc)
Gclc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
methotrexate 1 58.84 Quite High
Multiple sclerosis 4 54.16 Quite High
Bioavailability 2 36.56 Quite Low
gABA 18 5.00 Very Low Very Low Very Low
Dopamine 14 5.00 Very Low Very Low Very Low
Glutamate 13 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 24 84.84 Quite High
Pancreatitis 80 83.24 Quite High
Mitochondrial Disorders 5 82.56 Quite High
Cerebellar Diseases 9 73.36 Quite High
Miller Fisher Syndrome 2 68.52 Quite High
Sprains And Strains 8 59.32 Quite High
Demyelinating Disease 5 54.16 Quite High
Ataxia 73 50.48 Quite High
Enteropathy 1 42.48 Quite Low
Celiac Disease 1 33.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, quantitative real-time PCR was performed to monitor changes in GCLc and GCLm message abundance.
Regulation (changes) of GCLc
1) Confidence 0.22 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2639703 Disease Relevance 0.39 Pain Relevance 0
NAC is rapidly hydrolyzed and under the consecutive effects of gamma-glutamylcysteine synthetase and GSH synthetase, GSH is generated.
Regulation (effects) of gamma-glutamylcysteine synthetase
2) Confidence 0.04 Published 2010 Journal Current Neuropharmacology Section Body Doc Link PMC2866461 Disease Relevance 0.49 Pain Relevance 0.06

General Comments

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