INT261044

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.05
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CISH) intracellular (CISH) molecular_function (CISH)
cellular_component (CISH)
CHR (Homo sapiens)
CISH (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcium channel 34 100.00 Very High Very High Very High
antagonist 2 85.76 High High
Inflammation 20 5.00 Very Low Very Low Very Low
Catecholamine 12 5.00 Very Low Very Low Very Low
imagery 8 5.00 Very Low Very Low Very Low
medulla 8 5.00 Very Low Very Low Very Low
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 4 54.96 Quite High
INFLAMMATION 26 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Infection 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Fungal Infection 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hence, these findings indicate that CAT and CHR, being unable to evoke a Ca2+ mobilization from intracellular stores in absence of extracellular Ca2+, by their 2-APB sensitive induction of Ca2+ entry via SOCs may converge on iPLA2 in a manner similar to the two CaM inhibitors W7 and CMZ.


CHR Positive_regulation (induction) of SOCs associated with calcium channel
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2639705 Disease Relevance 0.05 Pain Relevance 0.18
CHR and CAT directly activate SOCs via iPLA2
CHR Positive_regulation (activate) of SOCs associated with calcium channel
2) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2639705 Disease Relevance 0 Pain Relevance 0.18

General Comments

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