INT261048

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.21
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CA2) extracellular space (CA2) lyase activity (CA2)
response to stress (CA2) cytoplasm (CA2)
CHR (Homo sapiens)
CA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcium channel 34 99.52 Very High Very High Very High
antagonist 2 85.76 High High
Inflammatory stimuli 4 76.16 Quite High
imagery 8 49.36 Quite Low
Inflammation 20 10.04 Low Low
Catecholamine 12 5.00 Very Low Very Low Very Low
medulla 8 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fungal Infection 2 83.76 Quite High
INFLAMMATION 26 75.84 Quite High
Shock 4 53.68 Quite High
Apoptosis 4 5.00 Very Low Very Low Very Low
Infection 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hence, these findings indicate that CAT and CHR, being unable to evoke a Ca2+ mobilization from intracellular stores in absence of extracellular Ca2+, by their 2-APB sensitive induction of Ca2+ entry via SOCs may converge on iPLA2 in a manner similar to the two CaM inhibitors W7 and CMZ.


CHR Positive_regulation (induction) of Ca2 associated with calcium channel
1) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2639705 Disease Relevance 0.05 Pain Relevance 0.18
In PMNs loaded with Fluo-3, a transient Ca2+ influx was induced by 20 µM of either CHR or CAT (20 µM) in the presence, but not in the absence, of 1 mM free extracellular Ca2+ (Figure 1A).
CHR Positive_regulation (induced) of Ca2
2) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2639705 Disease Relevance 0.16 Pain Relevance 0.04

General Comments

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