INT261077

Context Info Confidence 0.18 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0.10 Pain Relevance 0.27

CHR (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 20 95.44 imagery 8 90.40 Calcium channel 34 81.76 Catecholamine 12 37.64 Inflammatory stimuli 4 16.84 medulla 8 5.00 cytokine 2 5.00 Inflammatory response 2 5.00 Pain 2 5.00 metalloproteinase 2 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 26 95.44 Fungal Infection 2 24.44 Apoptosis 4 5.00 Shock 4 5.00 Infection 4 5.00 Pain 2 5.00 Death 2 5.00 Disease 2 5.00 Stress 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

With different concentrations of CHR or CAT (0–200 µM), the percentage of activated PMNs was concentration dependent, being maximal at 50 µM for CHR (45%) and CAT (60%), respectively (Figure 2B).

Localization (concentrations) of CHR

1) Confidence 0.18 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2639705 Disease Relevance 0 Pain Relevance 0.15

We finally analyzed by HPLC and Nano-LC MS-MS the material released by PMNs following stimulation by CHR and CAT.

Localization (released) of CHR

2) Confidence 0.17 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2639705 Disease Relevance 0.10 Pain Relevance 0.12

General Comments

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