INT261093

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.93
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (PLA2G6) cytoplasm (PLA2G6)
PLA2G6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcium channel 17 98.16 Very High Very High Very High
cytokine 64 92.28 High High
Inflammation 121 50.00 Quite Low
Inflammatory mediators 24 14.60 Low Low
Inflammatory response 12 9.40 Low Low
chemokine 17 5.00 Very Low Very Low Very Low
Catecholamine 6 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
bradykinin 6 5.00 Very Low Very Low Very Low
medulla 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Otitis Media With Effusion 92 96.76 Very High Very High Very High
Otitis Media 134 95.44 Very High Very High Very High
Hyperplasia 4 84.84 Quite High
Death 1 75.88 Quite High
Metaplasia 4 54.96 Quite High
INFLAMMATION 157 50.00 Quite Low
Infection 16 48.72 Quite Low
Cholesteatoma 48 5.00 Very Low Very Low Very Low
Adhesions 14 5.00 Very Low Very Low Very Low
Edema 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Displacement of CaM leads to iPLA2 activation and production of lysophospholipids inducing the opening of SOCs [36], the entry of Ca2+ and the release of innate immune factors among a long list of proteins (Figure 8C and Figures S1 and S2).
Positive_regulation (leads) of Gene_expression (production) of iPLA2 associated with calcium channel
1) Confidence 0.31 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2639705 Disease Relevance 0.08 Pain Relevance 0.05
enhances PLA2 expression (237).
Positive_regulation (enhances) of Gene_expression (expression) of PLA2
2) Confidence 0.08 Published 2008 Journal Clinical and Experimental Otorhinolaryngology Section Body Doc Link PMC2671742 Disease Relevance 0.86 Pain Relevance 0.05

General Comments

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