INT261123

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.00
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Casp8) peptidase activity (Casp8) mitochondrion (Casp8)
extracellular space (Tnfsf10) nucleus (Casp8) protein complex (Casp8)
Tnfsf10 (Mus musculus)
Casp8 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 8 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 13 99.40 Very High Very High Very High
Cancer 36 83.04 Quite High
Necrosis 2 63.44 Quite High
Glioma 20 62.64 Quite High
Brain Tumor 10 59.60 Quite High
Toxicity 3 31.12 Quite Low
Body Weight 6 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Glioblastoma 1 5.00 Very Low Very Low Very Low
Adenovirus Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similar to other TNF family members such as FasL and TNF-a, TRAIL activates caspase-8 as an initial apoptotic signaling event [10], [11].
TRAIL Positive_regulation (activates) of caspase-8 associated with apoptosis
1) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2641005 Disease Relevance 1.00 Pain Relevance 0

General Comments

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