INT261154

Context Info Confidence 0.25 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Title Documents 1 Total Number 1 Disease Relevance 0.32 Pain Relevance 0.18

mitochondrion (Aldh5a1) oxidoreductase activity (Aldh5a1)

Aldh5a1 (Mus musculus)

Pain Link Frequency Relevance Heat Neurotransmitter 4 99.98 gABA 51 93.04 GABAergic 3 29.64 Glutamate 5 5.00 imagery 3 5.00 antagonist 2 5.00 palliative 1 5.00 Central nervous system 1 5.00

Disease Link Frequency Relevance Heat Encephalopathy 2 88.36 Convulsion 9 84.84 Congenital Anomalies 6 5.00 Muscle Hypotonia 1 5.00 Epilepsy 1 5.00 Targeted Disruption 1 5.00 Death 1 5.00 Failure To Thrive 1 5.00 Frailty 1 5.00 Ataxia 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Neurotransmitter alterations in embryonic succinate semialdehyde dehydrogenase (SSADH) deficiency suggest a heightened excitatory state during development Background

Regulation (alterations) of Negative_regulation (deficiency) of SSADH associated with neurotransmitter

1) Confidence 0.25 Published 2008 Journal BMC Dev Biol Section Title Doc Link PMC2642797 Disease Relevance 0.32 Pain Relevance 0.18

General Comments

This test has worked.