INT261167

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Context Info
Confidence 0.75
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.16
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (GATM) small molecule metabolic process (GATM) embryo development (GATM)
cellular nitrogen compound metabolic process (GATM) cytoplasm (GATM)
Anatomy Link Frequency
embryo 1
GATM (Homo sapiens)
Pain Link Frequency Relevance Heat
gABA 102 94.48 High High
imagery 6 83.56 Quite High
Central nervous system 2 62.16 Quite High
Neurotransmitter 8 50.00 Quite Low
Glutamate 10 5.00 Very Low Very Low Very Low
GABAergic 6 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 12 84.12 Quite High
Convulsion 18 5.00 Very Low Very Low Very Low
Encephalopathy 4 5.00 Very Low Very Low Very Low
Muscle Hypotonia 2 5.00 Very Low Very Low Very Low
Epilepsy 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Failure To Thrive 2 5.00 Very Low Very Low Very Low
Frailty 2 5.00 Very Low Very Low Very Low
Ataxia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Braissant and colleagues [40] demonstrated that AGAT is expressed as early as E12.5 in rat hepatic primordial, and rapidly attains an adult expression pattern thereafter, verifying the importance of creatine formation in the developing embryo.
Gene_expression (expressed) of AGAT in embryo
1) Confidence 0.75 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2642797 Disease Relevance 0.07 Pain Relevance 0.26
GB is purported to derive through the catalytic action of the arginine glycine amidinotransferase (AGAT) reaction, which normally produces the creatine precursor guanidinoacetate from arginine and glycine.
Gene_expression (produces) of AGAT
2) Confidence 0.75 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2642797 Disease Relevance 0.08 Pain Relevance 0.21

General Comments

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