INT261232

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Ugt2b)
Anatomy Link Frequency
blood 1
Ugt2b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Desipramine 2 32.56 Quite Low
headache 6 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatotoxicity 4 94.88 High High
Crystal Associated Disease 54 50.00 Quite Low
Hyperuricemia 31 50.00 Quite Low
Hypertension 9 5.00 Very Low Very Low Very Low
Headache 6 5.00 Very Low Very Low Very Low
Metabolic Syndrome 4 5.00 Very Low Very Low Very Low
Renal Insufficiency 4 5.00 Very Low Very Low Very Low
Myocardial Infarction 4 5.00 Very Low Very Low Very Low
Adverse Drug Reaction 4 5.00 Very Low Very Low Very Low
Renal Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Febuxostat is highly bound to albumin in blood and is mainly metabolized by UDP-glucuronosyltransferase (UGT) 1 and 2 families and to a lesser extent by cytochrome P450 (CYP) enzymes.
Localization (metabolized) of UDP-glucuronosyltransferase in blood
1) Confidence 0.04 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2643102 Disease Relevance 0.18 Pain Relevance 0

General Comments

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