INT261276

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pde5a) signal transduction (Pde5a)
Pde5a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
potassium channel 1 95.76 Very High Very High Very High
Calcium channel 1 94.48 High High
Neuronal nitric oxide synthase 1 81.08 Quite High
Neurotransmitter 2 75.16 Quite High
fibrosis 5 5.00 Very Low Very Low Very Low
Angina 4 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 67.08 Quite High
Erectile Dysfunction 123 49.56 Quite Low
Reprotox - General 2 8 35.96 Quite Low
Disease 6 19.88 Low Low
Diabetes Mellitus 30 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 9 5.00 Very Low Very Low Very Low
Lower Urinary Tract Symptoms 8 5.00 Very Low Very Low Very Low
Benign Prostatic Hypertrophy 8 5.00 Very Low Very Low Very Low
Immunotherapy Of Cancer 8 5.00 Very Low Very Low Very Low
Fibrosis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increased concentration of cGMP activates protein kinase G, also called cGMP-dependent kinase, which through phosphorylation of ion channels opens potassium channels and inhibits calcium channels.
Positive_regulation (increased) of Positive_regulation (activates) of cGMP associated with calcium channel and potassium channel
1) Confidence 0.26 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2643112 Disease Relevance 0.07 Pain Relevance 0.21

General Comments

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