INT261352

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Context Info
Confidence 0.19
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.39
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ifi205)
Anatomy Link Frequency
Brain 1
Ifi205 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 35 100.00 Very High Very High Very High
agonist 1 65.76 Quite High
Inflammation 1 63.84 Quite High
midbrain 6 50.08 Quite High
Multiple sclerosis 5 27.52 Quite Low
gABA 16 5.00 Very Low Very Low Very Low
Locus ceruleus 10 5.00 Very Low Very Low Very Low
Action potential 7 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Somatostatin 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 220 96.76 Very High Very High Very High
Teratoma 4 93.96 High High
Encephalitis 1 64.32 Quite High
Myocardial Infarction 13 57.04 Quite High
Congenital Anomalies 44 50.00 Quite Low
Disease 26 48.00 Quite Low
Attention Deficit Hyperactivity Disorder 10 45.48 Quite Low
Apoptosis 13 44.64 Quite Low
Stress 15 32.64 Quite Low
Demyelinating Disease 5 27.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mouse ESC lines D3 [15] and Rosa26 [16] were stably transfected with DNA constructs allowing the expression of the green fluorescent protein (GFP) under the control of the mouse cardiac specific enhancer element of the Nkx2-5 transcription factor as previously described [14].
Gene_expression (transfected) of D3
1) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2902505 Disease Relevance 0.15 Pain Relevance 0
Brain-derived neurotrophic factor (BDNF), discussed below, controls the expression of DA D3 receptor, and a link has been proposed between BDNF and DA neurotransmission in schizophrenia.181

Peroxisome Proliferator–Activated Receptor gamma.

Gene_expression (expression) of D3 in Brain associated with dopamine and schizophrenia
2) Confidence 0.03 Published 2009 Journal Schizophrenia Bulletin Section Body Doc Link PMC2643957 Disease Relevance 0.24 Pain Relevance 0.54

General Comments

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