INT261372

Context Info Confidence 0.00 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.24 Pain Relevance 0.58

nucleus (Gsk3b, Ifi205) carbohydrate metabolic process (Gsk3b) protein complex (Gsk3b) response to stress (Gsk3b) cytoplasm (Gsk3b) cytosol (Gsk3b)

Anatomy Link Frequency Brain 2 Gsk3b (Rattus norvegicus) Ifi205 (Mus musculus)

Pain Link Frequency Relevance Heat Dopamine 35 100.00 agonist 1 65.76 Inflammation 1 63.84 midbrain 6 51.88 Multiple sclerosis 5 27.52 gABA 16 5.00 Locus ceruleus 10 5.00 Pain 6 5.00 Somatostatin 5 5.00 Hippocampus 5 5.00

Disease Link Frequency Relevance Heat Schizophrenia 220 96.76 Encephalitis 1 64.32 Congenital Anomalies 44 50.00 Disease 26 48.00 Attention Deficit Hyperactivity Disorder 10 47.28 Apoptosis 12 44.64 Stress 14 32.64 Demyelinating Disease 5 27.52 Neurodegenerative Disease 6 24.80 Autism 8 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Brain-derived neurotrophic factor (BDNF), discussed below, controls the expression of DA D3 receptor, and a link has been proposed between BDNF and DA neurotransmission in schizophrenia.181 Peroxisome Proliferator–Activated Receptor gamma.

factor Regulation (controls) of Gene_expression (expression) of D3 in Brain associated with dopamine and schizophrenia

1) Confidence 0.00 Published 2009 Journal Schizophrenia Bulletin Section Body Doc Link PMC2643957 Disease Relevance 0.24 Pain Relevance 0.58

General Comments

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