INT261381

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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (S100b) oxidoreductase activity (Nsdhl) endoplasmic reticulum (Nsdhl)
nucleus (S100b) cytoplasm (S100b)
Anatomy Link Frequency
astrocytes 2
Nsdhl (Mus musculus)
S100b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 3 79.44 Quite High
antagonist 2 67.24 Quite High
amygdala 2 61.36 Quite High
Hippocampus 5 58.96 Quite High
cytokine 2 29.72 Quite Low
Dopamine 35 5.00 Very Low Very Low Very Low
gABA 16 5.00 Very Low Very Low Very Low
Locus ceruleus 10 5.00 Very Low Very Low Very Low
midbrain 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 44 91.84 High High
Disease 26 83.32 Quite High
Schizophrenia 220 83.04 Quite High
Toxicity 4 79.80 Quite High
Urological Neuroanatomy 4 60.56 Quite High
Autoimmune Disease 4 33.48 Quite Low
Leukemia 1 21.44 Low Low
Stress 14 5.00 Very Low Very Low Very Low
Apoptosis 12 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BPA activates mouse astrocytes as shown by BPA induction of stellate morphology and increased GFAP.102 Nonylphenol, another commercial chemical identified as an endocrine disruptor, also increases GFAP in cultured rat hypothalamic cells.130 Although BPA's effect on S100B expression has not been reported, BPA does impact calcium homeostasis through other pathways discussed below.


BPA Regulation (effect) of Gene_expression (expression) of S100B in astrocytes
1) Confidence 0.06 Published 2009 Journal Schizophrenia Bulletin Section Body Doc Link PMC2643957 Disease Relevance 0.82 Pain Relevance 0.13

General Comments

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