INT261382

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) aging (Il6) extracellular region (Il6)
oxidoreductase activity (Nsdhl) endoplasmic reticulum (Nsdhl)
Anatomy Link Frequency
astrocytes 1
Nsdhl (Mus musculus)
Il6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 2 72.36 Quite High
nMDA receptor 3 26.48 Quite Low
Dopamine 35 5.00 Very Low Very Low Very Low
gABA 16 5.00 Very Low Very Low Very Low
Locus ceruleus 10 5.00 Very Low Very Low Very Low
midbrain 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Somatostatin 5 5.00 Very Low Very Low Very Low
Multiple sclerosis 5 5.00 Very Low Very Low Very Low
Hippocampus 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 220 97.86 Very High Very High Very High
Autoimmune Disease 4 71.00 Quite High
Congenital Anomalies 44 50.00 Quite Low
Cognitive Disorder 5 27.80 Quite Low
Disease 26 8.64 Low Low
Stress 14 5.00 Very Low Very Low Very Low
Apoptosis 12 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 10 5.00 Very Low Very Low Very Low
Autism 8 5.00 Very Low Very Low Very Low
Psychosis 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A shift to Th2 with reduced Th1 is usually observed in schizophrenia,291 which is the reverse of BPA exposure although interferon-gamma production has also been reported as either increased or decreased by BPA exposure.295,299 However, the maternal immune environment may be more important to the pathogenesis of schizophrenia through an immune response involving IL-6.300 In the section above concerning astrocytes, the stimulating effect of BPA on the effects of IL-6 (LIF) was discussed.
BPA Regulation (effect) of IL-6 in astrocytes associated with schizophrenia
1) Confidence 0.03 Published 2009 Journal Schizophrenia Bulletin Section Body Doc Link PMC2643957 Disease Relevance 0.66 Pain Relevance 0.04

General Comments

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