INT261383

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il4) extracellular region (Il4) oxidoreductase activity (Nsdhl)
endoplasmic reticulum (Nsdhl)
Anatomy Link Frequency
T cells 2
Nsdhl (Mus musculus)
Il4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 2 59.48 Quite High
nMDA receptor 3 13.60 Low Low
Dopamine 35 5.00 Very Low Very Low Very Low
gABA 16 5.00 Very Low Very Low Very Low
Locus ceruleus 10 5.00 Very Low Very Low Very Low
midbrain 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Somatostatin 5 5.00 Very Low Very Low Very Low
Multiple sclerosis 5 5.00 Very Low Very Low Very Low
Hippocampus 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 220 95.56 Very High Very High Very High
Congenital Anomalies 44 63.28 Quite High
Autoimmune Disease 4 58.12 Quite High
Disease 26 34.16 Quite Low
Cognitive Disorder 5 14.92 Low Low
Stress 14 5.00 Very Low Very Low Very Low
Apoptosis 12 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 10 5.00 Very Low Very Low Very Low
Autism 8 5.00 Very Low Very Low Very Low
Psychosis 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BPA also enhances IL-4 production by antigen-primed CD4+ T cells that is mediated by a Ca2+/calcineurin/nuclear factor-AT signaling pathway.299 Schizophrenia research has found a genetic association between altered calcineurin signaling with schizophrenia.305 The same research identified the early growth-responsive-3 (EGR-3) gene as the possible susceptibility gene.
BPA Positive_regulation (enhances) of Gene_expression (production) of IL-4 in T cells associated with schizophrenia
1) Confidence 0.03 Published 2009 Journal Schizophrenia Bulletin Section Body Doc Link PMC2643957 Disease Relevance 0.46 Pain Relevance 0.03

General Comments

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