INT261394

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.69
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Nsdhl) endoplasmic reticulum (Nsdhl)
Anatomy Link Frequency
brains 1
Nsdhl (Mus musculus)
nt (Mus musculus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 1 89.12 High High
midbrain 6 78.52 Quite High
Multiple sclerosis 5 72.80 Quite High
Hippocampus 5 72.32 Quite High
gABA 16 56.88 Quite High
antagonist 2 50.40 Quite High
long-term potentiation 1 13.12 Low Low
Inflammation 1 12.40 Low Low
agonist 1 11.28 Low Low
Dopamine 35 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Manic Depressive Disorder 5 98.38 Very High Very High Very High
Psychosis 7 98.18 Very High Very High Very High
Syndrome 4 97.46 Very High Very High Very High
Digeorge Syndrome 1 96.92 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 10 95.98 Very High Very High Very High
Repression 1 94.66 High High
Schizophrenia 220 94.20 High High
Cognitive Disorder 5 82.96 Quite High
Anaplastic Astrocytoma 1 74.72 Quite High
Death 5 74.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although genetic linkage studies have not demonstrated a clear relationship between schizophrenia and NT, the repression of a polymorphism of the NT gene is associated with ADHD.202 ADHD is a risk factor for velocardiofacial syndrome (22q11.2 deletion syndrome), which carries a risk of psychosis and mania.203 The effect of BPA on NT function has not been studied in animal brains, but BPA inhibits NT function in cultured bovine adrenal medullary cells.204

Choline Acetyltransferase.

BPA Negative_regulation (inhibits) of NT in brains associated with manic depressive disorder, psychosis, syndrome, repression, digeorge syndrome, attention deficit hyperactivity disorder and schizophrenia
1) Confidence 0.01 Published 2009 Journal Schizophrenia Bulletin Section Body Doc Link PMC2643957 Disease Relevance 1.69 Pain Relevance 0.24

General Comments

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