INT2614

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Context Info
Confidence 0.78
First Reported 1977
Last Reported 2011
Negated 5
Speculated 2
Reported most in Abstract
Documents 187
Total Number 192
Disease Relevance 105.89
Pain Relevance 24.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CGA) small molecule metabolic process (CGA) extracellular region (CGA)
cellular nitrogen compound metabolic process (CGA) cell-cell signaling (CGA)
Anatomy Link Frequency
follicle 19
embryo 8
CSF 5
pituitary 5
brain 4
CGA (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 199 100.00 Very High Very High Very High
Neuropeptide 32 100.00 Very High Very High Very High
Dopamine 27 100.00 Very High Very High Very High
Somatostatin 23 100.00 Very High Very High Very High
Dismenorea 63 99.84 Very High Very High Very High
Serotonin 20 99.66 Very High Very High Very High
cINOD 5 99.62 Very High Very High Very High
narcan 57 99.56 Very High Very High Very High
Enkephalin 7 99.48 Very High Very High Very High
Morphine 4 99.24 Very High Very High Very High
Disease Link Frequency Relevance Heat
Endometriosis (extended) 848 100.00 Very High Very High Very High
Cancer 642 99.98 Very High Very High Very High
Stomach Cancer 15 99.98 Very High Very High Very High
Reprotox - General 2 356 99.96 Very High Very High Very High
Anovulation 120 99.96 Very High Very High Very High
Metastasis 97 99.96 Very High Very High Very High
Large Cell Carcinoma 5 99.96 Very High Very High Very High
Congenital Anomalies 62 99.92 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 16 99.92 Very High Very High Very High
Adenoma 30 99.88 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A case of extragenital choriocarcinoma which produces human chorionic gonadotropin (HCG) in the small intestine of a 48-yr-old Japanese women is reported.
Gene_expression (produces) of HCG in small intestine associated with reprotox - general 1
1) Confidence 0.78 Published 1991 Journal Am. J. Gastroenterol. Section Abstract Doc Link 1858745 Disease Relevance 0.54 Pain Relevance 0.09
A 58-year-old male presented with a rare case of brain metastatic bronchogenic carcinoma with human chorionic gonadotropin (hCG) production causing cerebellar hemorrhage with symptoms of nausea, vomiting, and headache.
Gene_expression (production) of hCG in brain associated with bronchogenic carcinoma, vomiting, headache and cva
2) Confidence 0.77 Published 2001 Journal Neurol. Med. Chir. (Tokyo) Section Abstract Doc Link 11561353 Disease Relevance 1.30 Pain Relevance 0.25
The primary lesion of bronchogenic carcinoma showed choriocarcinomatous change because the tumor could produce hCG.
Gene_expression (produce) of hCG associated with bronchogenic carcinoma and cancer
3) Confidence 0.77 Published 2001 Journal Neurol. Med. Chir. (Tokyo) Section Abstract Doc Link 11561353 Disease Relevance 1.72 Pain Relevance 0.26
No serum tumor markers such as alpha-fetoprotein (AFP) and human chorionic gonadotropin (HCG) were detectable.
Gene_expression (detectable) of HCG associated with cancer
4) Confidence 0.77 Published 1991 Journal Neurol. Med. Chir. (Tokyo) Section Abstract Doc Link 1726235 Disease Relevance 1.59 Pain Relevance 0.09
No serum tumor markers such as alpha-fetoprotein (AFP) and human chorionic gonadotropin (HCG) were detectable.
Gene_expression (detectable) of chorionic gonadotropin associated with cancer
5) Confidence 0.77 Published 1991 Journal Neurol. Med. Chir. (Tokyo) Section Abstract Doc Link 1726235 Disease Relevance 1.60 Pain Relevance 0.09
No serum tumor markers such as alpha-fetoprotein or human chorionic gonadotropin were detectable.
Gene_expression (detectable) of chorionic gonadotropin associated with cancer
6) Confidence 0.75 Published 1999 Journal No Shinkei Geka Section Abstract Doc Link 10190163 Disease Relevance 1.54 Pain Relevance 0.19
It is suggested that the explanation for this may be that hCG production in many patients with ectopic pregnancies is normal until symptoms develop and falls thereafter as the functional trophoblastic mass is reduced by the shearing off the trophoblast from the tubal wall, which takes place with the development of the pregnancy and of symptoms.
Gene_expression (production) of hCG associated with ectopic pregnancy
7) Confidence 0.75 Published 1982 Journal Fertil. Steril. Section Abstract Doc Link 7067849 Disease Relevance 0.39 Pain Relevance 0.07
Of 39 patients without clinical signs of pregnancy, hCG was detectable in the serum in 3 women and PSBG in 11 others.
Gene_expression (detectable) of hCG
8) Confidence 0.75 Published 1980 Journal Obstet Gynecol Section Abstract Doc Link 6966042 Disease Relevance 0.72 Pain Relevance 0.07
[Gastric cancer producing AFP/HCG which had a rapidly progressive course with metastasis to the brain discovered postoperatively].
Gene_expression (producing) of HCG in brain associated with metastasis and stomach cancer
9) Confidence 0.72 Published 2007 Journal Nippon Shokakibyo Gakkai Zasshi Section Title Doc Link 17485946 Disease Relevance 0.72 Pain Relevance 0.08
Furthermore serum level of testosterone was decreased and levels of luteinizing hormone and follicle-stimulation hormone were within normal range.
Gene_expression (levels) of luteinizing hormone in follicle
10) Confidence 0.69 Published 2008 Journal Praxis Section Abstract Doc Link 19048508 Disease Relevance 0.60 Pain Relevance 0.30
A case of extragenital choriocarcinoma which produces human chorionic gonadotropin (HCG) in the small intestine of a 48-yr-old Japanese women is reported.
Gene_expression (produces) of gonadotropin in small intestine associated with reprotox - general 1
11) Confidence 0.68 Published 1991 Journal Am. J. Gastroenterol. Section Abstract Doc Link 1858745 Disease Relevance 0.54 Pain Relevance 0.09
Immunohistochemically, tumor cells were strongly positive for keratin, HCG, and focally positive for human placental lactogen.
Gene_expression (positive) of HCG associated with cancer
12) Confidence 0.67 Published 2010 Journal Virchows Arch. Section Abstract Doc Link 20013345 Disease Relevance 1.01 Pain Relevance 0.07
Metastatic bronchogenic carcinoma with human chorionic gonadotropin production manifesting as cerebellar hemorrhage--case report.
Gene_expression (production) of gonadotropin associated with bronchogenic carcinoma and cva
13) Confidence 0.67 Published 2001 Journal Neurol. Med. Chir. (Tokyo) Section Title Doc Link 11561353 Disease Relevance 1.73 Pain Relevance 0.26
A 58-year-old male presented with a rare case of brain metastatic bronchogenic carcinoma with human chorionic gonadotropin (hCG) production causing cerebellar hemorrhage with symptoms of nausea, vomiting, and headache.
Gene_expression (production) of gonadotropin in brain associated with bronchogenic carcinoma, vomiting, headache and cva
14) Confidence 0.67 Published 2001 Journal Neurol. Med. Chir. (Tokyo) Section Abstract Doc Link 11561353 Disease Relevance 1.30 Pain Relevance 0.25
The diagnosis of pregnancy by the detection of the human chorionic gonadotropin was initially described 53 years ago by Selmar Aschheim and Bernhardt Zondek.
Gene_expression (detection) of chorionic gonadotropin
15) Confidence 0.67 Published 1981 Journal Pediatr. Clin. North Am. Section Abstract Doc Link 7243371 Disease Relevance 0.84 Pain Relevance 0.14
Given the importance of the serum:CSF ratio of beta-HCG in this patient with no other evidence of intracranial disease, serial CSF analysis would allow analysis of the trend as blood is reabsorbed.
Gene_expression (ratio) of beta-HCG in blood associated with disease
16) Confidence 0.67 Published 2008 Journal J Med Case Reports Section Body Doc Link PMC2442118 Disease Relevance 1.37 Pain Relevance 0.18
A diagnostic technique not utilized in this case was serial CSF sampling for beta-HCG.
Gene_expression (sampling) of beta-HCG
17) Confidence 0.67 Published 2008 Journal J Med Case Reports Section Body Doc Link PMC2442118 Disease Relevance 1.33 Pain Relevance 0.18
Histological examination showed the resected tumor was large cell carcinoma. hCG was detected in the cerebrospinal fluid and was identified by immunohistochemical staining in tumor cells.
Gene_expression (detected) of hCG in cerebrospinal fluid associated with large cell carcinoma and cancer
18) Confidence 0.67 Published 2001 Journal Neurol. Med. Chir. (Tokyo) Section Abstract Doc Link 11561353 Disease Relevance 1.84 Pain Relevance 0.27
Improvements in the techniques for the measurement of human chorionic gonadotropin (hCG) have been directly related to the progress in the purification and isolation of hCG and elucidation of the amino acid sequence of the hormone-nonspecific alpha subunit and hormone-specific beta subunit of hCG.
Gene_expression (elucidation) of hCG
19) Confidence 0.67 Published 1981 Journal Pediatr. Clin. North Am. Section Abstract Doc Link 7243371 Disease Relevance 0.73 Pain Relevance 0.13
Improvements in the techniques for the measurement of human chorionic gonadotropin (hCG) have been directly related to the progress in the purification and isolation of hCG and elucidation of the amino acid sequence of the hormone-nonspecific alpha subunit and hormone-specific beta subunit of hCG.
Gene_expression (elucidation) of hCG
20) Confidence 0.67 Published 1981 Journal Pediatr. Clin. North Am. Section Abstract Doc Link 7243371 Disease Relevance 0.73 Pain Relevance 0.13

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